Paucity of natural killer and cytotoxic T cells in human neuromyelitis optica lesions
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چکیده
منابع مشابه
Paucity of natural killer and cytotoxic T cells in human neuromyelitis optica lesions.
Neuromyelitis optica is a severe inflammatory demyelinating disease of the central nervous system. Most patients with neuromyelitis optica have circulating immunoglobulin G (IgG) antibodies against the astrocytic water channel protein aquaporin-4 (AQP4), which are pathogenic. Anti-AQP4 IgG-mediated complement-dependent astrocyte toxicity is a key mechanism of central nervous system damage in ne...
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ژورنال
عنوان ژورنال: NeuroReport
سال: 2012
ISSN: 0959-4965
DOI: 10.1097/wnr.0b013e32835ab480